Custom Antibody Market by Service (Development, Purification, Labelling), Type (Monoclonal, Recombinant), Source (Rabbit, Mice), Application (Research, Therapeutics), Indication (Oncology, Immunology), End User (Biopharma, CROs) - Global Forecast to 2028", size is projected to reach USD 860 million by 2028 from 548 million in 2023, at a CAGR of 9.4% during the forecast period. Factors such as rising R&D funding and growing initiatives in custom antibody and increasing use of antibodies in biomarkers & validation are driving the growth of this market. However, challenges associated with the immunization of host animals are the major factors restraining the growth of this market.

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Key Market Players

The prominent players operating in the custom antibody market are Thermo Fisher Scientific Inc. (US), GenScript (China), Merck KGaA (Germany), Abcam (US), and Agilent Technologies, Inc. (US).

Custom Antibody Market Dynamics

DRIVERS: Increased Funding is likely to upsurge the market growth

Antibody development and research has gained momentum, owing to the depleting mAbs pipeline, rising incidence of chronic and debilitating disorders such as cancer and infectious diseases; and growing need to develop effective and promising cures for several diseases that adversely affect the quality of life across the globe. The continuous rise in the funding for antibody research by government agencies is further supporting the growth of this market. For instance, in April 2022, Japan invested USD 970 million in regenerative medicine, focusing on induced pluripotent stem cells (iPS) to survive with the world's oldest population. The stem cells can then be used to repair human tissues or grow organs, indirectly impacting antibody research in the country. The funding will enable the country to continue to support custom antibody startups and SMEs, strengthen the emerging asiatic bioeconomy and help unlock the societal benefits of custom antibody.

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RESTRAINTS: Cost and complexities associated with antibody

The development of antibodies requires detailed knowledge and qualitative considerations, which require high capital investments and time limitations. In addition, the technologies required for antibody production include large bioreactors, filtration systems, and media & buffers for upstream/ downstream processing and purification. Thus, on average, the cost to produce custom mAbs goes on increasing depending on the additional services required, based on the procedures followed by each player. While developing the site-specific antibody requires consideration of the antigen against which antibodies need to be generated, followed by their specificity and reproducibility. Thus, the cost associated with antibodies can potentially hamper the market growth to a certain extent.

OPPORTUNITIES: Emerging Markets

The rising investments by emerging countries in antibody drug discovery are responsible for the growth of the global market in the region. For instance, the Australian government has allocated USD 3.6 billion in basic research to support science, research, and innovation in the country from 2020 to 2021 to develop new products for treating lung conditions, including mepolizumab, a monoclonal antibody used to treat severe asthma. While the growing incidence of infectious and chronic disorders and increasing R&D initiatives to develop innovative treatment and diagnostic options are some of the factors likely to project the use of a custom antibody in the coming years. Additionally, developments in research infrastructure and the low-cost manufacturing advantage offered by emerging countries are expected to encourage market players to invest in emerging markets like Asia Pacific during the forecast period.

The antibody development segment dominated the custom antibody market in 2022.

Based on service, the market is broadly segmented into antibody development, antibody production & purification, and antibody labeling. In 2022, antibody development accounted for the dominant share of the global market. This segment & large share can be attributed to factors such as the rising incidence of cancer and other chronic diseases that are creating a high demand for therapeutic antibodies. Furthermore, key market players are investing in R&D in the market is likely to upsurge the growth of the segment.

Asia Pacific is likely to grow at double digit growth rate during the forecast period.

The Asia Pacific region is estimated to grow at the highest CAGR in the custom antibody market during the forecast period, this is mainly due to factors such the rising investment in research & development, increased adoption of custom antibodies for various research and diagnostics purpose, emergence of new market players in custom antibody market.

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