Malegra DXT is a combination medication used to treat two common male physical disorders: erectile dysfunction (ED) and PE. The onset of action for Malegra DXT varies, but Sildenafil Citrate typically starts working within 30 minutes to 1 hour after ingestion, while Duloxetine may take longer to reach peak effectiveness for PE. https://www.genericday.com/malegra-dxt.html